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Analytical Tools for the Study of Cellular Glycosylation in the Immune System

Overview of attention for article published in Frontiers in immunology, January 2013
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Title
Analytical Tools for the Study of Cellular Glycosylation in the Immune System
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00451
Pubmed ID
Authors

Yvette van Kooyk, Hakan Kalay, Juan J. Garcia-Vallejo

Abstract

It is becoming increasingly clear that glycosylation plays important role in intercellular communication within the immune system. Glycosylation-dependent interactions are crucial for the innate and adaptive immune system and regulate immune cell trafficking, synapse formation, activation, and survival. These functions take place by the cis or trans interaction of lectins with glycans. Classical immunological and biochemical methods have been used for the study of lectin function; however, the investigation of their counterparts, glycans, requires very specialized methodologies that have been extensively developed in the past decade within the Glycobiology scientific community. This mini-review intends to summarize the available technology for the study of glycan biosynthesis, its regulation and characterization for their application to the study of glycans in immunology.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 1%
United States 1 1%
Germany 1 1%
Argentina 1 1%
Unknown 68 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 28%
Student > Ph. D. Student 17 24%
Student > Bachelor 8 11%
Student > Master 8 11%
Professor 3 4%
Other 8 11%
Unknown 8 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 31 43%
Biochemistry, Genetics and Molecular Biology 13 18%
Immunology and Microbiology 8 11%
Medicine and Dentistry 4 6%
Chemistry 3 4%
Other 4 6%
Unknown 9 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2013.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Frontiers in immunology
#27,421
of 31,520 outputs
Outputs of similar age
#258,412
of 289,004 outputs
Outputs of similar age from Frontiers in immunology
#335
of 503 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,520 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,004 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.