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Debug Your Bugs – How NLRs Shape Intestinal Host-Microbe Interactions

Overview of attention for article published in Frontiers in immunology, January 2013
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  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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Title
Debug Your Bugs – How NLRs Shape Intestinal Host-Microbe Interactions
Published in
Frontiers in immunology, January 2013
DOI 10.3389/fimmu.2013.00479
Pubmed ID
Authors

Simone Lipinski, Philip Rosenstiel

Abstract

The host's ability to discriminate friend and foe and to establish a precise homeostasis with its associated microbiota is crucial for its survival and fitness. Among the mediators of intestinal host-microbe interactions, NOD-like receptor (NLR) proteins take center stage. They are present in the epithelial lining and innate immune cells that constantly monitor microbial activities at the intestinal barrier. Dysfunctional NLRs predispose to intestinal inflammation as well as sensitization to extra-intestinal immune-mediated diseases and are linked to the alteration of microbial communities. Here, we review advances in our understanding of their reciprocal relationship in the regulation of intestinal homeostasis and implications for intestinal health.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Germany 1 2%
India 1 2%
France 1 2%
Spain 1 2%
United Kingdom 1 2%
Unknown 54 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 31%
Student > Ph. D. Student 14 23%
Student > Master 10 16%
Other 3 5%
Professor > Associate Professor 3 5%
Other 8 13%
Unknown 4 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 43%
Immunology and Microbiology 9 15%
Medicine and Dentistry 8 13%
Biochemistry, Genetics and Molecular Biology 6 10%
Nursing and Health Professions 1 2%
Other 2 3%
Unknown 9 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2014.
All research outputs
#14,777,452
of 25,654,806 outputs
Outputs from Frontiers in immunology
#12,584
of 32,130 outputs
Outputs of similar age
#167,923
of 290,396 outputs
Outputs of similar age from Frontiers in immunology
#143
of 503 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 32,130 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,396 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 503 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.