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TLR Agonists as Modulators of the Innate Immune Response and Their Potential as Agents Against Infectious Disease

Overview of attention for article published in Frontiers in immunology, January 2014
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Title
TLR Agonists as Modulators of the Innate Immune Response and Their Potential as Agents Against Infectious Disease
Published in
Frontiers in immunology, January 2014
DOI 10.3389/fimmu.2014.00079
Pubmed ID
Authors

Edin J. Mifsud, Amabel C. L. Tan, David C. Jackson

Abstract

Immunotherapies that can either activate or suppress innate immune responses are being investigated as treatments against infectious diseases and the pathology they can cause. The objective of these therapies is to elicit protective immune responses thereby limiting the harm inflicted by the pathogen. The Toll-like receptor (TLR) signaling pathway plays critical roles in numerous host immune defenses and has been identified as an immunotherapeutic target against the consequences of infectious challenge. This review focuses on some of the recent advances being made in the development of TLR-ligands as potential prophylactic and/or therapeutic agents.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 203 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
France 1 <1%
Norway 1 <1%
United Kingdom 1 <1%
Canada 1 <1%
Unknown 198 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 42 21%
Researcher 37 18%
Student > Master 21 10%
Student > Bachelor 19 9%
Student > Doctoral Student 15 7%
Other 33 16%
Unknown 36 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 51 25%
Immunology and Microbiology 34 17%
Biochemistry, Genetics and Molecular Biology 27 13%
Medicine and Dentistry 25 12%
Chemistry 8 4%
Other 19 9%
Unknown 39 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2021.
All research outputs
#17,365,807
of 25,483,400 outputs
Outputs from Frontiers in immunology
#20,416
of 31,801 outputs
Outputs of similar age
#203,341
of 319,712 outputs
Outputs of similar age from Frontiers in immunology
#54
of 97 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,801 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,712 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 97 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.