Title |
MicroRNAs, Major Players in B Cells Homeostasis and Function
|
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Published in |
Frontiers in immunology, March 2014
|
DOI | 10.3389/fimmu.2014.00098 |
Pubmed ID | |
Authors |
Richard Danger, Faouzi Braza, Magali Giral, Jean-Paul Soulillou, Sophie Brouard |
Abstract |
As a main actor in humoral immunity, B cells participate in various antibody-related disorders. However, a deeper understanding of B-cell differentiation and function is needed in order to decipher their immune-modulatory roles, notably with the recent highlighting of regulatory B cells. microRNAs (miRNAs), key factors in various biological and pathological processes, have been shown to be essential for B-cell homeostasis, and therefore understanding their participation in B-cell biology could help identify biomarkers and contribute toward curing B-cell-related immune disorders. This review aims to report studies casting light on the roles played by miRNAs in B-cell lineage and function and B-cell-related immune pathologies. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 2 | 3% |
Japan | 1 | 1% |
Hungary | 1 | 1% |
France | 1 | 1% |
Unknown | 72 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 18 | 23% |
Researcher | 12 | 16% |
Student > Bachelor | 9 | 12% |
Student > Master | 9 | 12% |
Student > Doctoral Student | 7 | 9% |
Other | 7 | 9% |
Unknown | 15 | 19% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 15 | 19% |
Medicine and Dentistry | 14 | 18% |
Immunology and Microbiology | 3 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 1% |
Other | 2 | 3% |
Unknown | 17 | 22% |