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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Understanding the Biology of Antigen Cross-Presentation for the Design of Vaccines Against Cancer
|
|---|---|
| Published in |
Frontiers in immunology, April 2014
|
| DOI | 10.3389/fimmu.2014.00149 |
| Pubmed ID | |
| Authors |
Cynthia M. Fehres, Wendy W. J. Unger, Juan J. Garcia-Vallejo, Yvette van Kooyk |
| Abstract |
Antigen cross-presentation, the process in which exogenous antigens are presented on MHC class I molecules, is crucial for the generation of effector CD8(+) T cell responses. Although multiple cell types are being described to be able to cross-present antigens, in vivo this task is mainly carried out by certain subsets of dendritic cells (DCs). Aspects such as the internalization route, the pathway of endocytic trafficking, and the simultaneous activation through pattern-recognition receptors have a determining influence in how antigens are handled for cross-presentation by DCs. In this review, we will summarize new insights in factors that affect antigen cross-presentation of human DC subsets, and we will discuss the possibilities to exploit antigen cross-presentation for immunotherapy against cancer. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| United Kingdom | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 352 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 2 | <1% |
| Germany | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 348 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 79 | 22% |
| Student > Master | 53 | 15% |
| Researcher | 47 | 13% |
| Student > Bachelor | 45 | 13% |
| Student > Doctoral Student | 22 | 6% |
| Other | 54 | 15% |
| Unknown | 52 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 87 | 25% |
| Immunology and Microbiology | 62 | 18% |
| Biochemistry, Genetics and Molecular Biology | 47 | 13% |
| Medicine and Dentistry | 39 | 11% |
| Engineering | 18 | 5% |
| Other | 41 | 12% |
| Unknown | 58 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2023.
All research outputs
#3,346,181
of 25,394,764 outputs
Outputs from Frontiers in immunology
#3,649
of 31,554 outputs
Outputs of similar age
#32,691
of 241,593 outputs
Outputs of similar age from Frontiers in immunology
#14
of 135 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,554 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,593 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 135 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.