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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Organizing MHC Class II Presentation
|
|---|---|
| Published in |
Frontiers in immunology, April 2014
|
| DOI | 10.3389/fimmu.2014.00158 |
| Pubmed ID | |
| Authors |
David R. Fooksman |
| Abstract |
Major histocompatibility complex (MHC) class II molecules are ligands for CD4(+) T cells and are critical for initiating the adaptive immune response. This review is focused on what is currently known about MHC class II organization at the plasma membrane of antigen presenting cells and how this affects antigen presentation to T cells. The organization and diffusion of class II molecules have been measured by a variety of biochemical and microscopic techniques. Membrane lipids and other proteins have been implicated in MHC class II organization and function. However, when compared with the organization of MHC class I or TCR complexes, much less is known about MHC class II. Since clustering of T cell receptors occurs during activation, the organization of MHC molecules prior to recognition and during synapse formation may be critical for antigen presentation. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Switzerland | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 2% |
| United States | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 86 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 28% |
| Student > Master | 19 | 21% |
| Researcher | 15 | 17% |
| Student > Bachelor | 5 | 6% |
| Student > Postgraduate | 5 | 6% |
| Other | 11 | 12% |
| Unknown | 10 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 34 | 38% |
| Immunology and Microbiology | 12 | 13% |
| Biochemistry, Genetics and Molecular Biology | 10 | 11% |
| Medicine and Dentistry | 8 | 9% |
| Physics and Astronomy | 3 | 3% |
| Other | 10 | 11% |
| Unknown | 13 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2014.
All research outputs
#19,945,185
of 25,374,917 outputs
Outputs from Frontiers in immunology
#22,579
of 31,520 outputs
Outputs of similar age
#168,925
of 241,397 outputs
Outputs of similar age from Frontiers in immunology
#85
of 135 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,520 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,397 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 135 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.