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Microbe–Host Interactions are Positively and Negatively Regulated by Galectin–Glycan Interactions

Overview of attention for article published in Frontiers in immunology, June 2014
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Title
Microbe–Host Interactions are Positively and Negatively Regulated by Galectin–Glycan Interactions
Published in
Frontiers in immunology, June 2014
DOI 10.3389/fimmu.2014.00284
Pubmed ID
Authors

Linda G. Baum, Omai B. Garner, Katrin Schaefer, Benhur Lee

Abstract

Microbe-host interactions are complex processes that are directly and indirectly regulated by a variety of factors, including microbe presentation of specific molecular signatures on the microbial surface, as well as host cell presentation of receptors that recognize these pathogen signatures. Cell surface glycans are one important class of microbial signatures that are recognized by a variety of host cell lectins. Host cell lectins that recognize microbial glycans include members of the galectin family of lectins that recognize specific glycan ligands on viruses, bacteria, fungi, and parasites. In this review, we will discuss the ways that the interactions of microbial glycans with host cell galectins positively and negatively regulate pathogen attachment, invasion, and survival, as well as regulate host responses that mitigate microbial pathogenesis.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 3 5%
United States 1 2%
United Kingdom 1 2%
Unknown 61 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 33%
Researcher 7 11%
Student > Master 7 11%
Student > Doctoral Student 5 8%
Other 5 8%
Other 12 18%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 32%
Biochemistry, Genetics and Molecular Biology 14 21%
Chemistry 8 12%
Immunology and Microbiology 7 11%
Engineering 2 3%
Other 3 5%
Unknown 11 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2014.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Frontiers in immunology
#27,421
of 31,520 outputs
Outputs of similar age
#208,948
of 242,961 outputs
Outputs of similar age from Frontiers in immunology
#120
of 146 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,520 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,961 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 146 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.