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MCL and Mincle: C-Type Lectin Receptors That Sense Damaged Self and Pathogen-Associated Molecular Patterns

Overview of attention for article published in Frontiers in immunology, June 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

twitter
3 X users
facebook
1 Facebook page
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
109 Dimensions

Readers on

mendeley
152 Mendeley
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Title
MCL and Mincle: C-Type Lectin Receptors That Sense Damaged Self and Pathogen-Associated Molecular Patterns
Published in
Frontiers in immunology, June 2014
DOI 10.3389/fimmu.2014.00288
Pubmed ID
Authors

Mark B. Richardson, Spencer J. Williams

Abstract

Macrophage C-type lectin (MCL) and macrophage inducible C-type lectin (Mincle) comprise part of an extensive repertoire of pattern recognition receptors with the ability to sense damage-associated and pathogen-associated molecular patterns. In this review, we cover the discovery and molecular characterization of these C-type lectin receptors, and highlight recent advances in the understanding of their roles in orchestrating the response of the immune system to bacterial and fungal infection, and damaged self. We also discuss the identification and structure-activity relationships of activating ligands, particularly trehalose dimycolate and related mycobacterial glycolipids, which have significant potential in the development of TH1/TH17 vaccination strategies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Australia 1 <1%
Unknown 150 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 32 21%
Researcher 26 17%
Student > Master 17 11%
Student > Bachelor 17 11%
Student > Doctoral Student 11 7%
Other 21 14%
Unknown 28 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 36 24%
Biochemistry, Genetics and Molecular Biology 25 16%
Immunology and Microbiology 24 16%
Chemistry 15 10%
Medicine and Dentistry 12 8%
Other 11 7%
Unknown 29 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 December 2019.
All research outputs
#6,875,368
of 25,373,627 outputs
Outputs from Frontiers in immunology
#7,288
of 31,516 outputs
Outputs of similar age
#61,717
of 243,358 outputs
Outputs of similar age from Frontiers in immunology
#26
of 140 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,358 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.