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Fasting Induces IL-1 Resistance and Free-Fatty Acid-Mediated Up-Regulation of IL-1R2 and IL-1RA

Overview of attention for article published in Frontiers in immunology, July 2014
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  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

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Title
Fasting Induces IL-1 Resistance and Free-Fatty Acid-Mediated Up-Regulation of IL-1R2 and IL-1RA
Published in
Frontiers in immunology, July 2014
DOI 10.3389/fimmu.2014.00315
Pubmed ID
Authors

Jennifer J. Joesting, Morgan L. Moon, Stephen J. Gainey, Brittany L. Tisza, Neil A. Blevins, Gregory G. Freund

Abstract

Weight-loss is a near societal obsession and many diet programs use significant calorie restriction including fasting/short term starvation to generate rapid effects. Fasting is also a well-recognized cause of immunosuppression especially within the innate immune system. In this study, we sought to determine if the IL-1 arm of the neuroimmune system was down-regulated by a 24 h fast and how fasting might generate this effect.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 46 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 17%
Student > Ph. D. Student 7 15%
Researcher 7 15%
Student > Master 7 15%
Student > Doctoral Student 2 4%
Other 7 15%
Unknown 9 19%
Readers by discipline Count As %
Medicine and Dentistry 10 21%
Biochemistry, Genetics and Molecular Biology 8 17%
Agricultural and Biological Sciences 7 15%
Neuroscience 7 15%
Immunology and Microbiology 1 2%
Other 3 6%
Unknown 11 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2014.
All research outputs
#15,168,964
of 25,373,627 outputs
Outputs from Frontiers in immunology
#14,207
of 31,516 outputs
Outputs of similar age
#121,047
of 240,612 outputs
Outputs of similar age from Frontiers in immunology
#55
of 140 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,612 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.