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Organ-Specific and Memory Treg Cells: Specificity, Development, Function, and Maintenance

Overview of attention for article published in Frontiers in immunology, July 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

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7 X users
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1 patent

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164 Mendeley
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Title
Organ-Specific and Memory Treg Cells: Specificity, Development, Function, and Maintenance
Published in
Frontiers in immunology, July 2014
DOI 10.3389/fimmu.2014.00333
Pubmed ID
Authors

Iris K. Gratz, Daniel J. Campbell

Abstract

Foxp3(+) regulatory T cells (Treg cells) are essential for establishing and maintaining self-tolerance, and also inhibit immune responses to innocuous environmental antigens. Imbalances and dysfunction in Treg cells lead to a variety of immune-mediated diseases, as deficits in Treg cell function contribute to the development autoimmune disease and pathological tissue damage, whereas overabundance of Treg cells can promote chronic infection and tumorigenesis. Recent studies have highlighted the fact that Treg cells themselves are a diverse collection of phenotypically and functionally specialized populations, with distinct developmental origins, antigen-specificities, tissue-tropisms, and homeostatic requirements. The signals directing the differentiation of these populations, their specificities and the mechanisms by which they combine to promote organ-specific and systemic tolerance, and how they embody the emerging property of regulatory memory are the focus of this review.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 164 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Hungary 1 <1%
Italy 1 <1%
Germany 1 <1%
Mexico 1 <1%
United Kingdom 1 <1%
Unknown 157 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 46 28%
Researcher 24 15%
Student > Master 16 10%
Student > Bachelor 15 9%
Student > Doctoral Student 8 5%
Other 34 21%
Unknown 21 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 50 30%
Medicine and Dentistry 32 20%
Immunology and Microbiology 26 16%
Biochemistry, Genetics and Molecular Biology 21 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 1%
Other 6 4%
Unknown 27 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2014.
All research outputs
#4,807,631
of 25,371,288 outputs
Outputs from Frontiers in immunology
#5,294
of 31,507 outputs
Outputs of similar age
#44,238
of 241,650 outputs
Outputs of similar age from Frontiers in immunology
#18
of 141 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,507 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,650 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 141 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.