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Identification of Protective Antigens for Vaccination against Systemic Salmonellosis

Overview of attention for article published in Frontiers in immunology, August 2014
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Title
Identification of Protective Antigens for Vaccination against Systemic Salmonellosis
Published in
Frontiers in immunology, August 2014
DOI 10.3389/fimmu.2014.00381
Pubmed ID
Authors

Dirk Bumann

Abstract

There is an urgent medical need for improved vaccines with broad serovar coverage and high efficacy against systemic salmonellosis. Subunit vaccines offer excellent safety profiles but require identification of protective antigens, which remains a challenging task. Here, I review crucial properties of Salmonella antigens that might help to narrow down the number of potential candidates from more than 4000 proteins encoded in Salmonella genomes, to a more manageable number of 50-200 most promising antigens. I also discuss complementary approaches for antigen identification and potential limitations of current pre-clinical vaccine testing.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Uruguay 1 2%
Germany 1 2%
Brazil 1 2%
Unknown 38 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 39%
Researcher 12 29%
Professor > Associate Professor 2 5%
Student > Master 2 5%
Lecturer 1 2%
Other 1 2%
Unknown 7 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 29%
Immunology and Microbiology 9 22%
Biochemistry, Genetics and Molecular Biology 5 12%
Medicine and Dentistry 4 10%
Veterinary Science and Veterinary Medicine 1 2%
Other 1 2%
Unknown 9 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2014.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Frontiers in immunology
#22,570
of 31,513 outputs
Outputs of similar age
#167,605
of 242,843 outputs
Outputs of similar age from Frontiers in immunology
#94
of 145 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,513 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,843 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 145 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.