Title |
The Role of Extracellular Vesicles in Modulating the Host Immune Response during Parasitic Infections
|
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Published in |
Frontiers in immunology, September 2014
|
DOI | 10.3389/fimmu.2014.00433 |
Pubmed ID | |
Authors |
Sergio Montaner, Alicia Galiano, María Trelis, Lorena Martin-Jaular, Hernando A. del Portillo, Dolores Bernal, Antonio Marcilla |
Abstract |
Parasites are the cause of major diseases affecting billions of people. As the inflictions caused by these parasites affect mainly developing countries, they are considered as neglected diseases. These parasitic infections are often chronic and lead to significant immunomodulation of the host immune response by the parasite, which could benefit both the parasite and the host and are the result of millions of years of co-evolution. The description of parasite extracellular vesicles (EVs) in protozoa and helminths suggests that they may play an important role in host-parasite communication. In this review, recent studies on parasitic (protozoa and helminths) EVs are presented and their potential use as novel therapeutical approaches is discussed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Germany | 1 | <1% |
Argentina | 1 | <1% |
Switzerland | 1 | <1% |
Unknown | 219 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 39 | 17% |
Student > Master | 36 | 16% |
Student > Bachelor | 33 | 15% |
Researcher | 26 | 12% |
Student > Doctoral Student | 16 | 7% |
Other | 29 | 13% |
Unknown | 44 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 57 | 26% |
Biochemistry, Genetics and Molecular Biology | 42 | 19% |
Immunology and Microbiology | 32 | 14% |
Veterinary Science and Veterinary Medicine | 11 | 5% |
Medicine and Dentistry | 11 | 5% |
Other | 17 | 8% |
Unknown | 53 | 24% |