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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Many Unknowns Concerning the Bioenergetics of Exhaustion and Senescence during Chronic Viral Infection
|
|---|---|
| Published in |
Frontiers in immunology, September 2014
|
| DOI | 10.3389/fimmu.2014.00468 |
| Pubmed ID | |
| Authors |
Anna Schurich, Sian M. Henson |
| Abstract |
The immune system cannot be continuously reactivated throughout the lifetime of an organism; there is a finite point at which repeated antigenic challenge leads to the loss of lymphocyte function or the cells themselves. Antigen-specific T cells can be compromised in two ways through the distinct processes of replicative senescence and exhaustion. Senescence is initiated by a DNA damage response whereas exhaustion triggers inhibitory receptors to dampen the immune response. These two distinct pathways not only differ in their initiation but also growing evidence suggests that their biogenergetics is also different. Here, we review recent findings uncovering the metabolism of these unique states. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 2% |
| Unknown | 53 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 20% |
| Student > Ph. D. Student | 10 | 19% |
| Student > Master | 8 | 15% |
| Student > Doctoral Student | 7 | 13% |
| Student > Postgraduate | 4 | 7% |
| Other | 9 | 17% |
| Unknown | 5 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 16 | 30% |
| Agricultural and Biological Sciences | 15 | 28% |
| Biochemistry, Genetics and Molecular Biology | 9 | 17% |
| Medicine and Dentistry | 7 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 5 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 February 2016.
All research outputs
#15,090,466
of 25,371,288 outputs
Outputs from Frontiers in immunology
#13,905
of 31,513 outputs
Outputs of similar age
#130,637
of 263,052 outputs
Outputs of similar age from Frontiers in immunology
#74
of 176 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,513 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,052 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 176 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.