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Environmental and Metabolic Sensors That Control T Cell Biology

Overview of attention for article published in Frontiers in immunology, March 2015
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Title
Environmental and Metabolic Sensors That Control T Cell Biology
Published in
Frontiers in immunology, March 2015
DOI 10.3389/fimmu.2015.00099
Pubmed ID
Authors

George Ramsay, Doreen Cantrell

Abstract

The T lymphocyte response to pathogens is shaped by the microenvironment. Environmental sensors in T cells include the nutrient-sensing serine/threonine kinases, adenosine monophosphate-activated protein kinase and mammalian target of rapamycin complex 1. Other environmental sensors are transcription factors such as hypoxia-inducible factor-1 and the aryl hydrocarbon receptor. The present review explores the molecular basis for the impact of environmental signals on the differentiation of conventional T cell receptor αβ T cells and how the T cell response to immune stimuli can coordinate the T cell response to environmental cues.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
United States 1 <1%
Sweden 1 <1%
Unknown 107 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 28 25%
Student > Ph. D. Student 24 22%
Student > Master 11 10%
Student > Doctoral Student 8 7%
Professor 8 7%
Other 17 15%
Unknown 14 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 25%
Immunology and Microbiology 23 21%
Medicine and Dentistry 21 19%
Biochemistry, Genetics and Molecular Biology 12 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 4 4%
Unknown 21 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2015.
All research outputs
#19,942,887
of 25,373,627 outputs
Outputs from Frontiers in immunology
#22,570
of 31,513 outputs
Outputs of similar age
#203,040
of 291,952 outputs
Outputs of similar age from Frontiers in immunology
#111
of 160 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,513 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 291,952 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 160 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.