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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Shigella Manipulates Host Immune Responses by Delivering Effector Proteins with Specific Roles
|
|---|---|
| Published in |
Frontiers in immunology, May 2015
|
| DOI | 10.3389/fimmu.2015.00219 |
| Pubmed ID | |
| Authors |
Hiroshi Ashida, Hitomi Mimuro, Chihiro Sasakawa |
| Abstract |
The intestinal epithelium deploys multiple defense systems against microbial infection to sense bacterial components and danger alarms, as well as to induce intracellular signal transduction cascades that trigger both the innate and the adaptive immune systems, which are pivotal for bacterial elimination. However, many enteric bacterial pathogens, including Shigella, deliver a subset of virulence proteins (effectors) via the type III secretion system (T3SS) that enable bacterial evasion from host immune systems; consequently, these pathogens are able to efficiently colonize the intestinal epithelium. In this review, we present and select recently discovered examples of interactions between Shigella and host immune responses, with particular emphasis on strategies that bacteria use to manipulate inflammatory outputs of host-cell responses such as cell death, membrane trafficking, and innate and adaptive immune responses. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 201 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Portugal | 1 | <1% |
| Unknown | 198 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 34 | 17% |
| Student > Bachelor | 32 | 16% |
| Student > Master | 28 | 14% |
| Researcher | 23 | 11% |
| Student > Doctoral Student | 10 | 5% |
| Other | 23 | 11% |
| Unknown | 51 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 48 | 24% |
| Agricultural and Biological Sciences | 40 | 20% |
| Immunology and Microbiology | 32 | 16% |
| Medicine and Dentistry | 10 | 5% |
| Environmental Science | 3 | 1% |
| Other | 14 | 7% |
| Unknown | 54 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 May 2015.
All research outputs
#22,834,739
of 25,461,852 outputs
Outputs from Frontiers in immunology
#27,577
of 31,698 outputs
Outputs of similar age
#239,615
of 279,366 outputs
Outputs of similar age from Frontiers in immunology
#149
of 176 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,698 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,366 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 176 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.