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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Emerging and Novel Functions of Complement Protein C1q
|
|---|---|
| Published in |
Frontiers in immunology, June 2015
|
| DOI | 10.3389/fimmu.2015.00317 |
| Pubmed ID | |
| Authors |
Lubna Kouser, Shanmuga Priyaa Madhukaran, Abhishek Shastri, Anuvinder Saraon, Janez Ferluga, Maha Al-Mozaini, Uday Kishore |
| Abstract |
Complement protein C1q, the recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. It can bind various ligands derived from self, non-self, and altered self and modulate the functions of immune and non-immune cells including dendritic cells and microglia. C1q involvement in the clearance of apoptotic cells and subsequent B cell tolerance is more established now. Recent evidence appears to suggest that C1q plays an important role in pregnancy where its deficiency and dysregulation can have adverse effects, leading to preeclampsia, missed abortion, miscarriage or spontaneous loss, and various infections. C1q is also produced locally in the central nervous system, and has a protective role against pathogens and possible inflammatory functions while interacting with aggregated proteins leading to neurodegenerative diseases. C1q role in synaptic pruning, and thus CNS development, its anti-cancer effects as an immune surveillance molecule, and possibly in aging are currently areas of extensive research. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 17% |
| Unknown | 5 | 83% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 67% |
| Scientists | 1 | 17% |
| Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 237 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | <1% |
| Singapore | 1 | <1% |
| Unknown | 235 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 51 | 22% |
| Researcher | 37 | 16% |
| Student > Master | 26 | 11% |
| Student > Bachelor | 25 | 11% |
| Other | 14 | 6% |
| Other | 40 | 17% |
| Unknown | 44 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 46 | 19% |
| Medicine and Dentistry | 40 | 17% |
| Biochemistry, Genetics and Molecular Biology | 30 | 13% |
| Immunology and Microbiology | 27 | 11% |
| Neuroscience | 19 | 8% |
| Other | 28 | 12% |
| Unknown | 47 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2023.
All research outputs
#1,891,915
of 25,373,627 outputs
Outputs from Frontiers in immunology
#1,777
of 31,516 outputs
Outputs of similar age
#23,273
of 277,933 outputs
Outputs of similar age from Frontiers in immunology
#8
of 173 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,933 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 173 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.