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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction
|
|---|---|
| Published in |
Frontiers in immunology, July 2015
|
| DOI | 10.3389/fimmu.2015.00365 |
| Pubmed ID | |
| Authors |
Noëlla Lopes, Arnauld Sergé, Pierre Ferrier, Magali Irla |
| Abstract |
The thymus ensures the generation of a functional and highly diverse T-cell repertoire. The thymic medulla, which is mainly composed of medullary thymic epithelial cells (mTECs) and dendritic cells (DCs), provides a specialized microenvironment dedicated to the establishment of T-cell tolerance. mTECs play a privileged role in this pivotal process by their unique capacity to express a broad range of peripheral self-antigens that are presented to developing T cells. Reciprocally, developing T cells control mTEC differentiation and organization. These bidirectional interactions are commonly referred to as thymic crosstalk. This review focuses on the relative contributions of mTEC and DC subsets to the deletion of autoreactive T cells and the generation of natural regulatory T cells. We also summarize current knowledge regarding how hematopoietic cells conversely control the composition and complex three-dimensional organization of the thymic medulla. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 124 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 24 | 19% |
| Student > Ph. D. Student | 23 | 19% |
| Researcher | 16 | 13% |
| Student > Bachelor | 10 | 8% |
| Student > Doctoral Student | 5 | 4% |
| Other | 16 | 13% |
| Unknown | 30 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 39 | 31% |
| Agricultural and Biological Sciences | 26 | 21% |
| Biochemistry, Genetics and Molecular Biology | 17 | 14% |
| Medicine and Dentistry | 6 | 5% |
| Engineering | 2 | 2% |
| Other | 7 | 6% |
| Unknown | 27 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2015.
All research outputs
#15,755,393
of 25,394,764 outputs
Outputs from Frontiers in immunology
#15,396
of 31,554 outputs
Outputs of similar age
#140,606
of 275,666 outputs
Outputs of similar age from Frontiers in immunology
#76
of 164 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,554 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 275,666 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 164 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.