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Endogenous Antigen Presentation of MHC Class II Epitopes through Non-Autophagic Pathways

Overview of attention for article published in Frontiers in immunology, September 2015
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Title
Endogenous Antigen Presentation of MHC Class II Epitopes through Non-Autophagic Pathways
Published in
Frontiers in immunology, September 2015
DOI 10.3389/fimmu.2015.00464
Pubmed ID
Authors

Carol S. K. Leung

Abstract

Antigenic peptides presented by major histocompatibility complex (MHC) class II molecules are generally derived from exogenous proteins acquired by antigen presenting cells. However, in some circumstances, MHC class II molecules can present intracellular proteins expressed within the antigen-presenting cells. There are several described pathways by which endogenous antigens are degraded and gain access to MHC class II molecules. These include autophagy and other non-autophagic pathways; the latter category includes the MHC class I-like pathways, heat shock protein 90-mediated pathways, and internalization from the plasma membrane. This review will summarize and discuss the non-autophagic pathways.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 103 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 22%
Student > Bachelor 17 17%
Researcher 13 13%
Student > Master 10 10%
Student > Doctoral Student 7 7%
Other 9 9%
Unknown 24 23%
Readers by discipline Count As %
Immunology and Microbiology 22 21%
Agricultural and Biological Sciences 21 20%
Biochemistry, Genetics and Molecular Biology 20 19%
Medicine and Dentistry 9 9%
Veterinary Science and Veterinary Medicine 2 2%
Other 5 5%
Unknown 24 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2015.
All research outputs
#20,656,161
of 25,374,647 outputs
Outputs from Frontiers in immunology
#24,741
of 31,516 outputs
Outputs of similar age
#205,232
of 279,891 outputs
Outputs of similar age from Frontiers in immunology
#122
of 160 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,891 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 160 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.