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Inflammasome/IL-1β Responses to Streptococcal Pathogens

Overview of attention for article published in Frontiers in immunology, October 2015
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59 Mendeley
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Title
Inflammasome/IL-1β Responses to Streptococcal Pathogens
Published in
Frontiers in immunology, October 2015
DOI 10.3389/fimmu.2015.00518
Pubmed ID
Authors

Christopher N. LaRock, Victor Nizet

Abstract

Inflammation mediated by the inflammasome and the cytokine IL-1β are some of the earliest and most important alarms to infection. These pathways are responsive to the virulence factors that pathogens use to subvert immune processes, and thus are typically activated only by microbes with potential to cause severe disease. Among the most serious human infections are those caused by the pathogenic streptococci, in part because these species numerous strategies for immune evasion. Since the virulence factor armament of each pathogen is unique, the role of IL-1β and the pathways leading to its activation varies for each infection. This review summarizes the role of IL-1β during infections caused by streptococcal pathogens, with emphasis on emergent mechanisms and concepts countering paradigms determined for other organisms.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Norway 1 2%
Unknown 58 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 24%
Researcher 9 15%
Student > Bachelor 7 12%
Student > Master 7 12%
Professor > Associate Professor 4 7%
Other 8 14%
Unknown 10 17%
Readers by discipline Count As %
Immunology and Microbiology 14 24%
Agricultural and Biological Sciences 13 22%
Biochemistry, Genetics and Molecular Biology 7 12%
Medicine and Dentistry 6 10%
Chemistry 2 3%
Other 4 7%
Unknown 13 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2018.
All research outputs
#15,983,535
of 25,374,647 outputs
Outputs from Frontiers in immunology
#16,441
of 31,516 outputs
Outputs of similar age
#153,455
of 290,039 outputs
Outputs of similar age from Frontiers in immunology
#80
of 161 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,039 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 161 others from the same source and published within six weeks on either side of this one. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.