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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Bacterial Exotoxins and the Inflammasome
|
|---|---|
| Published in |
Frontiers in immunology, November 2015
|
| DOI | 10.3389/fimmu.2015.00570 |
| Pubmed ID | |
| Authors |
Allison J. Greaney, Stephen H. Leppla, Mahtab Moayeri |
| Abstract |
The inflammasomes are intracellular protein complexes that play an important role in innate immune sensing. Activation of inflammasomes leads to activation of caspase-1 and maturation and secretion of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18. In certain myeloid cells, this activation can also lead to an inflammatory cell death (pyroptosis). Inflammasome sensor proteins have evolved to detect a range of microbial ligands and bacterial exotoxins either through direct interaction or by detection of host cell changes elicited by these effectors. Bacterial exotoxins activate the inflammasomes through diverse processes, including direct sensor cleavage, modulation of ion fluxes through plasma membrane pore formation, and perturbation of various host cell functions. In this review, we summarize the findings on some of the bacterial exotoxins that activate the inflammasomes. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 14% |
| Switzerland | 1 | 14% |
| Unknown | 5 | 71% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 86% |
| Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Unknown | 90 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 22% |
| Researcher | 16 | 18% |
| Student > Master | 13 | 14% |
| Student > Bachelor | 10 | 11% |
| Professor | 4 | 4% |
| Other | 8 | 9% |
| Unknown | 20 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 19 | 21% |
| Agricultural and Biological Sciences | 17 | 19% |
| Biochemistry, Genetics and Molecular Biology | 17 | 19% |
| Medicine and Dentistry | 7 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
| Other | 6 | 7% |
| Unknown | 20 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2022.
All research outputs
#8,194,992
of 25,394,764 outputs
Outputs from Frontiers in immunology
#9,930
of 31,554 outputs
Outputs of similar age
#96,104
of 294,424 outputs
Outputs of similar age from Frontiers in immunology
#43
of 147 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 31,554 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 294,424 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 147 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.