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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Macrophage Switch in Obesity Development
|
|---|---|
| Published in |
Frontiers in immunology, January 2016
|
| DOI | 10.3389/fimmu.2015.00637 |
| Pubmed ID | |
| Authors |
Angela Castoldi, Cristiane Naffah de Souza, Niels Olsen Saraiva Câmara, Pedro M. Moraes-Vieira |
| Abstract |
Immune cell infiltration in (white) adipose tissue (AT) during obesity is associated with the development of insulin resistance. In AT, the main population of leukocytes are macrophages. Macrophages can be classified into two major populations: M1, classically activated macrophages, and M2, alternatively activated macrophages, although recent studies have identified a broad range of macrophage subsets. During obesity, AT M1 macrophage numbers increase and correlate with AT inflammation and insulin resistance. Upon activation, pro-inflammatory M1 macrophages induce aerobic glycolysis. By contrast, in lean humans and mice, the number of M2 macrophages predominates. M2 macrophages secrete anti-inflammatory cytokines and utilize oxidative metabolism to maintain AT homeostasis. Here, we review the immunologic and metabolic functions of AT macrophages and their different facets in obesity and the metabolic syndrome. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 12% |
| Switzerland | 2 | 12% |
| Mexico | 1 | 6% |
| France | 1 | 6% |
| Japan | 1 | 6% |
| Malaysia | 1 | 6% |
| Canada | 1 | 6% |
| Unknown | 8 | 47% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 65% |
| Scientists | 4 | 24% |
| Practitioners (doctors, other healthcare professionals) | 2 | 12% |
Mendeley readers
The data shown below were compiled from readership statistics for 597 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Chile | 1 | <1% |
| Sweden | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 592 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 92 | 15% |
| Student > Ph. D. Student | 90 | 15% |
| Student > Bachelor | 71 | 12% |
| Researcher | 61 | 10% |
| Student > Doctoral Student | 47 | 8% |
| Other | 73 | 12% |
| Unknown | 163 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 121 | 20% |
| Agricultural and Biological Sciences | 77 | 13% |
| Immunology and Microbiology | 62 | 10% |
| Medicine and Dentistry | 62 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 24 | 4% |
| Other | 54 | 9% |
| Unknown | 197 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2023.
All research outputs
#1,592,375
of 25,394,764 outputs
Outputs from Frontiers in immunology
#1,418
of 31,554 outputs
Outputs of similar age
#26,973
of 400,199 outputs
Outputs of similar age from Frontiers in immunology
#3
of 133 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,554 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,199 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 133 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.