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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Natural Killer Cell Recognition of Melanoma: New Clues for a More Effective Immunotherapy
|
|---|---|
| Published in |
Frontiers in immunology, January 2016
|
| DOI | 10.3389/fimmu.2015.00649 |
| Pubmed ID | |
| Authors |
Raquel Tarazona, Esther Duran, Rafael Solana |
| Abstract |
Natural killer (NK) cells participate in the early immune response against melanoma and also contribute to the development of an adequate adaptive immune response by their crosstalk with dendritic cells and cytokine secretion. Melanoma resistance to conventional therapies together with its high immunogenicity justifies the development of novel therapies aimed to stimulate effective immune responses against melanoma. However, melanoma cells frequently escape to CD8 T cell recognition by the down-regulation of major histocompatibility complex (MHC) class I molecules. In this scenario, NK cells emerge as potential candidates for melanoma immunotherapy due to their capacity to recognize and destroy melanoma cells expressing low levels of MHC class I molecules. In addition, the possibility to combine immune checkpoint blockade with other NK cell potentiating strategies (e.g., cytokine induction of activating receptors) has opened new perspectives in the potential use of adoptive NK cell-based immunotherapy in melanoma. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 17% |
| Unknown | 5 | 83% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 110 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 15% |
| Student > Ph. D. Student | 15 | 14% |
| Student > Master | 15 | 14% |
| Student > Bachelor | 8 | 7% |
| Student > Doctoral Student | 7 | 6% |
| Other | 19 | 17% |
| Unknown | 30 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 21 | 19% |
| Biochemistry, Genetics and Molecular Biology | 19 | 17% |
| Medicine and Dentistry | 12 | 11% |
| Agricultural and Biological Sciences | 11 | 10% |
| Engineering | 4 | 4% |
| Other | 8 | 7% |
| Unknown | 35 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2016.
All research outputs
#7,797,987
of 25,432,721 outputs
Outputs from Frontiers in immunology
#9,083
of 31,647 outputs
Outputs of similar age
#113,752
of 400,360 outputs
Outputs of similar age from Frontiers in immunology
#45
of 133 outputs
Altmetric has tracked 25,432,721 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 31,647 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,360 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 133 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.