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New Insights into Neutrophil Extracellular Traps: Mechanisms of Formation and Role in Inflammation

Overview of attention for article published in Frontiers in immunology, August 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

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8 X users
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1 patent
wikipedia
4 Wikipedia pages

Citations

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243 Dimensions

Readers on

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419 Mendeley
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Title
New Insights into Neutrophil Extracellular Traps: Mechanisms of Formation and Role in Inflammation
Published in
Frontiers in immunology, August 2016
DOI 10.3389/fimmu.2016.00302
Pubmed ID
Authors

Hang Yang, Mona Helena Biermann, Jan Markus Brauner, Yi Liu, Yi Zhao, Martin Herrmann

Abstract

Recent data suggest that NETosis plays a crucial role in the innate immune response and disturbs the homeostasis of the immune system. NETosis is a form of neutrophil-specific cell death characterized by the release of large web-like structures referred to as neutrophil extracellular traps (NETs). NETs are composed of DNA strands associated with histones and decorated with about 20 different proteins, including neutrophil elastase, myeloperoxidase, cathepsin G, proteinase 3, high mobility group protein B1, and LL37. Reportedly, NETosis can be induced by several microbes, and particulate matter including sterile stimuli, via distinct cellular mechanisms. Meanwhile, suicidal NETosis and vital NETosis are controversial. As we enter the second decade of research on NETosis, we have partly understood NETs as double-edged swords of innate immunity. In this review, we will discuss the mechanisms of NETosis, its antimicrobial action, and role in autoimmune diseases, as well as the relatively new field of NET-associated mitochondrial DNA.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 419 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
United States 1 <1%
Sweden 1 <1%
Poland 1 <1%
Unknown 415 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 59 14%
Student > Master 57 14%
Student > Bachelor 53 13%
Researcher 49 12%
Student > Doctoral Student 28 7%
Other 60 14%
Unknown 113 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 80 19%
Immunology and Microbiology 57 14%
Medicine and Dentistry 56 13%
Agricultural and Biological Sciences 41 10%
Pharmacology, Toxicology and Pharmaceutical Science 16 4%
Other 43 10%
Unknown 126 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2022.
All research outputs
#3,713,898
of 25,394,764 outputs
Outputs from Frontiers in immunology
#4,151
of 31,554 outputs
Outputs of similar age
#64,454
of 369,280 outputs
Outputs of similar age from Frontiers in immunology
#20
of 126 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,554 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,280 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 126 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.