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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Ectopic Lymphoid Structures: Powerhouse of Autoimmunity
|
|---|---|
| Published in |
Frontiers in immunology, October 2016
|
| DOI | 10.3389/fimmu.2016.00430 |
| Pubmed ID | |
| Authors |
Elisa Corsiero, Alessandra Nerviani, Michele Bombardieri, Costantino Pitzalis |
| Abstract |
Ectopic lymphoid structures (ELS) often develop at sites of inflammation in target tissues of autoimmune diseases, such as rheumatoid arthritis, Sjögren's syndrome, multiple sclerosis, myasthenia gravis, and systemic lupus erythematosus. ELS are characterized by the formation of organized T/B cells aggregates, which can acquire follicular dendritic cells network supporting an ectopic germinal center response. In this review, we shall summarize the mechanisms that regulate the formation of ELS in tertiary lymphoid organs, with particular emphasis on the role of lymphoid chemokines in both formation and maintenance of ELS, the role of emerging positive and negative regulators of ELS development and function, including T follicular helper cells and IL-27, respectively. Finally, we shall discuss the main functions of ELS in supporting the affinity maturation, clonal selection, and differentiation of autoreactive B cells contributing to the maintenance and perpetuation of humoral autoimmunity. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 4 | 33% |
| Sweden | 1 | 8% |
| Unknown | 7 | 58% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 67% |
| Practitioners (doctors, other healthcare professionals) | 3 | 25% |
| Scientists | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 185 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 183 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 46 | 25% |
| Researcher | 31 | 17% |
| Student > Master | 21 | 11% |
| Student > Bachelor | 20 | 11% |
| Other | 8 | 4% |
| Other | 21 | 11% |
| Unknown | 38 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 38 | 21% |
| Biochemistry, Genetics and Molecular Biology | 31 | 17% |
| Medicine and Dentistry | 30 | 16% |
| Agricultural and Biological Sciences | 18 | 10% |
| Neuroscience | 10 | 5% |
| Other | 19 | 10% |
| Unknown | 39 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2017.
All research outputs
#4,817,997
of 25,411,814 outputs
Outputs from Frontiers in immunology
#5,320
of 31,614 outputs
Outputs of similar age
#73,556
of 323,053 outputs
Outputs of similar age from Frontiers in immunology
#33
of 193 outputs
Altmetric has tracked 25,411,814 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,614 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,053 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 193 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.