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NETopathies? Unraveling the Dark Side of Old Diseases through Neutrophils

Overview of attention for article published in Frontiers in immunology, January 2017
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Title
NETopathies? Unraveling the Dark Side of Old Diseases through Neutrophils
Published in
Frontiers in immunology, January 2017
DOI 10.3389/fimmu.2016.00678
Pubmed ID
Authors

Alexandros Mitsios, Athanasios Arampatzioglou, Stella Arelaki, Ioannis Mitroulis, Konstantinos Ritis

Abstract

Neutrophil extracellular traps (NETs) were initially described as an antimicrobial mechanism of neutrophils. Over the last decade, several lines of evidence support the involvement of NETs in a plethora of pathological conditions. Clinical and experimental data indicate that NET release constitutes a shared mechanism, which is involved in a different degree in various manifestations of non-infectious diseases. Even though the backbone of NETs is similar, there are differences in their protein load in different diseases, which represent alterations in neutrophil protein expression in distinct disorder-specific microenvironments. The characterization of NET protein load in different NET-driven disorders could be of significant diagnostic and/or therapeutic value. Additionally, it will provide further evidence for the role of NETs in disease pathogenesis, and it will enable the characterization of disorders in which neutrophils and NET-dependent inflammation are of critical importance.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 <1%
Unknown 106 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 17%
Student > Ph. D. Student 16 15%
Other 11 10%
Student > Bachelor 11 10%
Student > Master 8 7%
Other 19 18%
Unknown 24 22%
Readers by discipline Count As %
Immunology and Microbiology 23 21%
Biochemistry, Genetics and Molecular Biology 18 17%
Medicine and Dentistry 16 15%
Agricultural and Biological Sciences 12 11%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Other 7 7%
Unknown 28 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2017.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Frontiers in immunology
#27,417
of 31,516 outputs
Outputs of similar age
#364,523
of 423,600 outputs
Outputs of similar age from Frontiers in immunology
#315
of 348 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,516 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 423,600 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 348 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.