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Type I Interferons and Natural Killer Cell Regulation in Cancer

Overview of attention for article published in Frontiers in immunology, March 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

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14 X users
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3 patents

Citations

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117 Dimensions

Readers on

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164 Mendeley
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Title
Type I Interferons and Natural Killer Cell Regulation in Cancer
Published in
Frontiers in immunology, March 2017
DOI 10.3389/fimmu.2017.00304
Pubmed ID
Authors

Lena Müller, Petra Aigner, Dagmar Stoiber

Abstract

Type I interferons (IFNs) are known to mediate antitumor effects against several tumor types and have therefore been commonly used in clinical anticancer treatment. However, how IFN signaling exerts its beneficial effects is only partially understood. The clinically relevant activity of type I IFNs has been mainly attributed to their role in tumor immune surveillance. Different mechanisms have been postulated to explain how type I IFNs stimulate the immune system. On the one hand, they modulate innate immune cell subsets such as natural killer (NK) cells. On the other hand, type I IFNs also influence adaptive immune responses. Here, we review evidence for the impact of type I IFNs on immune surveillance against cancer and highlight the role of NK cells therein.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 164 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 164 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 40 24%
Researcher 21 13%
Student > Master 19 12%
Student > Bachelor 13 8%
Student > Doctoral Student 12 7%
Other 16 10%
Unknown 43 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 35 21%
Immunology and Microbiology 24 15%
Medicine and Dentistry 22 13%
Agricultural and Biological Sciences 19 12%
Engineering 5 3%
Other 10 6%
Unknown 49 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2023.
All research outputs
#3,075,196
of 25,703,943 outputs
Outputs from Frontiers in immunology
#3,215
of 32,216 outputs
Outputs of similar age
#53,491
of 324,832 outputs
Outputs of similar age from Frontiers in immunology
#56
of 425 outputs
Altmetric has tracked 25,703,943 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32,216 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,832 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 425 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.