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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Dual Role of Fas/FasL-Mediated Signal in Peripheral Immune Tolerance
|
|---|---|
| Published in |
Frontiers in immunology, April 2017
|
| DOI | 10.3389/fimmu.2017.00403 |
| Pubmed ID | |
| Authors |
Akiko Yamada, Rieko Arakaki, Masako Saito, Yasusei Kudo, Naozumi Ishimaru |
| Abstract |
Fas-mediated apoptosis contributes to physiological and pathological cellular processes, such as differentiation and survival. In particular, the roles of Fas in immune cells are complex and critical for the maintenance of immune tolerance. The precise pathways and unique functions associated with Fas/FasL-mediated signaling in the immune system are known. The dual character of Fas/FasL-mediated immune regulation that induces beneficial or harmful effects is associated with the onset or development of immune disorders. Studies on mutations in genes encoding Fas and FasL gene of humans and mice contributed to our understanding of the pathogenesis of autoimmune diseases. Here, we review the opposing functions of Fas/FasL-mediated signaling, bilateral effects of Fas/FasL on in immune cells, and complex pathogenesis of autoimmunity mediated by Fas/FasL. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 33% |
| United States | 1 | 33% |
| Switzerland | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 248 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 248 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 44 | 18% |
| Student > Ph. D. Student | 41 | 17% |
| Student > Master | 28 | 11% |
| Researcher | 13 | 5% |
| Student > Doctoral Student | 10 | 4% |
| Other | 29 | 12% |
| Unknown | 83 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 61 | 25% |
| Immunology and Microbiology | 33 | 13% |
| Medicine and Dentistry | 25 | 10% |
| Agricultural and Biological Sciences | 22 | 9% |
| Neuroscience | 6 | 2% |
| Other | 16 | 6% |
| Unknown | 85 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2017.
All research outputs
#16,725,651
of 25,382,440 outputs
Outputs from Frontiers in immunology
#18,341
of 31,531 outputs
Outputs of similar age
#197,006
of 324,569 outputs
Outputs of similar age from Frontiers in immunology
#316
of 415 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,531 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,569 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 415 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.