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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Eosinophils in Autoimmune Diseases
|
|---|---|
| Published in |
Frontiers in immunology, April 2017
|
| DOI | 10.3389/fimmu.2017.00484 |
| Pubmed ID | |
| Authors |
Nicola L. Diny, Noel R. Rose, Daniela Čiháková |
| Abstract |
Eosinophils are multifunctional granulocytes that contribute to initiation and modulation of inflammation. Their role in asthma and parasitic infections has long been recognized. Growing evidence now reveals a role for eosinophils in autoimmune diseases. In this review, we summarize the function of eosinophils in inflammatory bowel diseases, neuromyelitis optica, bullous pemphigoid, autoimmune myocarditis, primary biliary cirrhosis, eosinophilic granulomatosis with polyangiitis, and other autoimmune diseases. Clinical studies, eosinophil-targeted therapies, and experimental models have contributed to our understanding of the regulation and function of eosinophils in these diseases. By examining the role of eosinophils in autoimmune diseases of different organs, we can identify common pathogenic mechanisms. These include degranulation of cytotoxic granule proteins, induction of antibody-dependent cell-mediated cytotoxicity, release of proteases degrading extracellular matrix, immune modulation through cytokines, antigen presentation, and prothrombotic functions. The association of eosinophilic diseases with autoimmune diseases is also examined, showing a possible increase in autoimmune diseases in patients with eosinophilic esophagitis, hypereosinophilic syndrome, and non-allergic asthma. Finally, we summarize key future research needs. |
X Demographics
The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 29% |
| Venezuela, Bolivarian Republic of | 3 | 14% |
| Mexico | 2 | 10% |
| Argentina | 1 | 5% |
| Ecuador | 1 | 5% |
| Uruguay | 1 | 5% |
| Unknown | 7 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 20 | 95% |
| Scientists | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 180 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 178 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 26 | 14% |
| Researcher | 25 | 14% |
| Student > Ph. D. Student | 22 | 12% |
| Other | 19 | 11% |
| Student > Master | 14 | 8% |
| Other | 34 | 19% |
| Unknown | 40 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 59 | 33% |
| Immunology and Microbiology | 24 | 13% |
| Biochemistry, Genetics and Molecular Biology | 15 | 8% |
| Agricultural and Biological Sciences | 13 | 7% |
| Neuroscience | 6 | 3% |
| Other | 16 | 9% |
| Unknown | 47 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2021.
All research outputs
#2,194,051
of 25,382,440 outputs
Outputs from Frontiers in immunology
#2,129
of 31,531 outputs
Outputs of similar age
#40,355
of 323,433 outputs
Outputs of similar age from Frontiers in immunology
#38
of 411 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,531 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,433 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 411 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.