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X Demographics
Mendeley readers
Attention Score in Context
| Title |
NK Cell Exhaustion
|
|---|---|
| Published in |
Frontiers in immunology, June 2017
|
| DOI | 10.3389/fimmu.2017.00760 |
| Pubmed ID | |
| Authors |
Jiacheng Bi, Zhigang Tian |
| Abstract |
Natural killer cells are important effector lymphocytes of the innate immune system, playing critical roles in antitumor and anti-infection host defense. Tumor progression or chronic infections, however, usually leads to exhaustion of NK cells, thus limiting the antitumor/infection potential of NK cells. In many tumors or chronic infections, multiple mechanisms might contribute to the exhaustion of NK cells, such as dysregulated NK cell receptors signaling, as well as suppressive effects by regulatory cells or soluble factors within the microenvironment. Better understanding of the characteristics, as well as the underlying mechanisms of NK cell exhaustion, not only should increase our understanding of the basic biology of NK cells but also could reveal novel NK cell-based antitumor/infection targets. Here, we provide an overview of our current knowledge on NK cell exhaustion in tumors, and in chronic infections. |
X Demographics
The data shown below were collected from the profiles of 132 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 13 | 10% |
| United States | 7 | 5% |
| United Kingdom | 2 | 2% |
| Japan | 2 | 2% |
| Portugal | 2 | 2% |
| South Africa | 1 | <1% |
| Italy | 1 | <1% |
| Switzerland | 1 | <1% |
| Canada | 1 | <1% |
| Other | 2 | 2% |
| Unknown | 100 | 76% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 120 | 91% |
| Scientists | 9 | 7% |
| Practitioners (doctors, other healthcare professionals) | 3 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 368 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 368 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 79 | 21% |
| Researcher | 55 | 15% |
| Student > Master | 48 | 13% |
| Student > Bachelor | 35 | 10% |
| Student > Doctoral Student | 15 | 4% |
| Other | 37 | 10% |
| Unknown | 99 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 87 | 24% |
| Biochemistry, Genetics and Molecular Biology | 63 | 17% |
| Agricultural and Biological Sciences | 40 | 11% |
| Medicine and Dentistry | 32 | 9% |
| Engineering | 8 | 2% |
| Other | 32 | 9% |
| Unknown | 106 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 75. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 January 2024.
All research outputs
#577,115
of 25,729,842 outputs
Outputs from Frontiers in immunology
#522
of 32,274 outputs
Outputs of similar age
#12,032
of 329,317 outputs
Outputs of similar age from Frontiers in immunology
#10
of 403 outputs
Altmetric has tracked 25,729,842 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32,274 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,317 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 403 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.