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Macrophage Inducible C-Type Lectin As a Multifunctional Player in Immunity

Overview of attention for article published in Frontiers in immunology, July 2017
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

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108 Mendeley
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Title
Macrophage Inducible C-Type Lectin As a Multifunctional Player in Immunity
Published in
Frontiers in immunology, July 2017
DOI 10.3389/fimmu.2017.00861
Pubmed ID
Authors

Emmanuel C. Patin, Selinda Jane Orr, Ulrich E. Schaible

Abstract

The macrophage-inducible C-type lectin (Mincle) is an innate immune receptor on myeloid cells sensing diverse entities including pathogens and damaged cells. Mincle was first described as a receptor for the mycobacterial cell wall glycolipid, trehalose-6,6'-dimycolate, or cord factor, and the mammalian necrotic cell-derived alarmin histone deacetylase complex unit Sin3-associated protein 130. Upon engagement by its ligands, Mincle induces secretion of innate cytokines and other immune mediators modulating inflammation and immunity. Since its discovery more than 25 years ago, the understanding of Mincle's immune function has made significant advances in recent years. In addition to mediating immune responses to infectious agents, Mincle has been linked to promote tumor progression, autoimmunity, and sterile inflammation; however, further studies are required to completely unravel the complex role of Mincle in these distinct host responses. In this review, we discuss recent findings on Mincle's biology with an emphasis on its diverse functions in immunity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 108 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 17%
Student > Ph. D. Student 17 16%
Researcher 14 13%
Student > Master 13 12%
Student > Doctoral Student 7 6%
Other 15 14%
Unknown 24 22%
Readers by discipline Count As %
Immunology and Microbiology 18 17%
Biochemistry, Genetics and Molecular Biology 16 15%
Agricultural and Biological Sciences 16 15%
Medicine and Dentistry 10 9%
Chemistry 9 8%
Other 13 12%
Unknown 26 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 November 2023.
All research outputs
#7,208,166
of 25,382,440 outputs
Outputs from Frontiers in immunology
#8,110
of 31,531 outputs
Outputs of similar age
#106,231
of 327,041 outputs
Outputs of similar age from Frontiers in immunology
#125
of 423 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 31,531 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,041 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 423 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.