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Sepsis-Induced Cardiomyopathy: Mechanisms and Treatments

Overview of attention for article published in Frontiers in immunology, August 2017
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Title
Sepsis-Induced Cardiomyopathy: Mechanisms and Treatments
Published in
Frontiers in immunology, August 2017
DOI 10.3389/fimmu.2017.01021
Pubmed ID
Authors

Yan-Cun Liu, Mu-Ming Yu, Song-Tao Shou, Yan-Fen Chai

Abstract

Sepsis is a lethal syndrome with a high incidence and a weighty economy burden. The pathophysiology of sepsis includes inflammation, immune dysfunction, and dysfunction of coagulation, while sepsis-induced cardiomyopathy (SIC), defined as a global but reversible dysfunction of both sides of the heart induced by sepsis, plays a significant role in all of the aspects above in the pathogenesis of sepsis. The complex pathogenesis of SIC involves a combination of dysregulation of inflammatory mediators, mitochondrial dysfunction, oxidative stress, disorder of calcium regulation, autonomic nervous system dysregulation, and endothelial dysfunction. The treatments for SIC include the signal pathway intervention, Chinese traditional medicine, and other specific therapy. Here, we reviewed the latest literatures on the mechanisms and treatments of SIC and hope to provide further insights to researchers and create a new road for the therapy of sepsis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 90 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 13 14%
Student > Master 12 13%
Student > Bachelor 9 10%
Researcher 8 9%
Student > Ph. D. Student 6 7%
Other 15 17%
Unknown 27 30%
Readers by discipline Count As %
Medicine and Dentistry 35 39%
Immunology and Microbiology 6 7%
Pharmacology, Toxicology and Pharmaceutical Science 6 7%
Biochemistry, Genetics and Molecular Biology 5 6%
Nursing and Health Professions 3 3%
Other 9 10%
Unknown 26 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2020.
All research outputs
#16,725,651
of 25,382,440 outputs
Outputs from Frontiers in immunology
#18,341
of 31,537 outputs
Outputs of similar age
#196,833
of 324,941 outputs
Outputs of similar age from Frontiers in immunology
#305
of 445 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,941 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 445 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.