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Follicular CD8+ T Cells: Origin, Function and Importance during HIV Infection

Overview of attention for article published in Frontiers in immunology, September 2017
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Title
Follicular CD8+ T Cells: Origin, Function and Importance during HIV Infection
Published in
Frontiers in immunology, September 2017
DOI 10.3389/fimmu.2017.01241
Pubmed ID
Authors

Federico Perdomo-Celis, Natalia Andrea Taborda, María Teresa Rugeles

Abstract

The lymphoid follicle is critical for the development of humoral immune responses. Cell circulation to this site is highly regulated by the differential expression of chemokine receptors. This feature contributes to the establishment of viral reservoirs in lymphoid follicles and the development of some types of malignancies that are able to evade immune surveillance, especially conventional CD8(+) T cells. Interestingly, a subtype of CD8(+) T cells located within the lymphoid follicle (follicular CD8(+) T cells) was recently described; these cells have been proposed to play an important role in viral and tumor control, as well as to modulate humoral and T follicular helper cell responses. In this review, we summarize the knowledge on this novel CD8(+) T cell population, its origin, function, and potential role in health and disease, in particular, in the context of the infection by the human immunodeficiency virus.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 75 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 19%
Researcher 8 11%
Student > Doctoral Student 8 11%
Student > Bachelor 6 8%
Student > Master 6 8%
Other 10 13%
Unknown 23 31%
Readers by discipline Count As %
Immunology and Microbiology 20 27%
Agricultural and Biological Sciences 12 16%
Biochemistry, Genetics and Molecular Biology 10 13%
Medicine and Dentistry 3 4%
Computer Science 1 1%
Other 3 4%
Unknown 26 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2017.
All research outputs
#20,663,600
of 25,382,440 outputs
Outputs from Frontiers in immunology
#24,755
of 31,537 outputs
Outputs of similar age
#255,548
of 329,378 outputs
Outputs of similar age from Frontiers in immunology
#445
of 525 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,378 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 525 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.