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Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond

Overview of attention for article published in Frontiers in immunology, November 2017
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Title
Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
Published in
Frontiers in immunology, November 2017
DOI 10.3389/fimmu.2017.01530
Pubmed ID
Authors

Cecília Jacques Gonçalves de Almeida

Abstract

Caveolins, encoded by the CAV gene family, are the main protein components of caveolae. In most tissues, caveolin-1 (Cav-1) and caveolin-2 (Cav-2) are co-expressed, and Cav-2 targeting to caveolae depends on the formation of heterooligomers with Cav-1. Notwithstanding, Cav-2 has unpredictable activities, opposing Cav-1 in the regulation of some cellular processes. While the major roles of Cav-1 as a modulator of cell signaling in inflammatory processes and in immune responses have been extensively discussed elsewhere, the aim of this review is to focus on data revealing the distinct activity of Cav-1 and Cav-2, which suggest that these proteins act antagonistically to fine-tune a variety of cellular processes relevant to inflammation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 70 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 17%
Student > Bachelor 12 17%
Student > Ph. D. Student 11 16%
Researcher 6 9%
Other 5 7%
Other 6 9%
Unknown 18 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 16 23%
Agricultural and Biological Sciences 9 13%
Medicine and Dentistry 9 13%
Neuroscience 5 7%
Immunology and Microbiology 3 4%
Other 10 14%
Unknown 18 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 December 2017.
All research outputs
#20,663,600
of 25,382,440 outputs
Outputs from Frontiers in immunology
#24,755
of 31,537 outputs
Outputs of similar age
#333,513
of 438,959 outputs
Outputs of similar age from Frontiers in immunology
#478
of 568 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 438,959 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 568 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.