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Leprosy As a Complex Infection: Breakdown of the Th1 and Th2 Immune Paradigm in the Immunopathogenesis of the Disease

Overview of attention for article published in Frontiers in immunology, November 2017
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

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4 X users
facebook
1 Facebook page
wikipedia
2 Wikipedia pages

Citations

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56 Dimensions

Readers on

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141 Mendeley
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Title
Leprosy As a Complex Infection: Breakdown of the Th1 and Th2 Immune Paradigm in the Immunopathogenesis of the Disease
Published in
Frontiers in immunology, November 2017
DOI 10.3389/fimmu.2017.01635
Pubmed ID
Authors

Jorge Rodrigues de Sousa, Mirian Nacagami Sotto, Juarez Antonio Simões Quaresma

Abstract

Leprosy is a chronic infectious disease whose evolution involves complex immune mechanisms of the host that influence the clinical presentation of the disease. For many years, the main interpretation of the host defense response was based on characterization of the established immune paradigm between T helper (Th) 1 and Th2 lymphocytes. However, with advances in the knowledge of immunology, new approaches have emerged along with the development of new immunological pathways that have changed the interpretation of the long-established paradigm of the polar forms of the disease, especially with the identification of new subtypes of T lymphocytes such as Th9, Th17, Th22, and Tregs. Thus, this review discusses the role of these new subtypes of T helper lymphocytes and how the development of the immune response of these cells modifies the pattern of the Th1/Th2 response in the immunopathogenesis of leprosy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 141 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 27 19%
Student > Master 16 11%
Researcher 12 9%
Student > Doctoral Student 11 8%
Student > Ph. D. Student 7 5%
Other 23 16%
Unknown 45 32%
Readers by discipline Count As %
Medicine and Dentistry 27 19%
Biochemistry, Genetics and Molecular Biology 13 9%
Agricultural and Biological Sciences 13 9%
Immunology and Microbiology 10 7%
Nursing and Health Professions 7 5%
Other 21 15%
Unknown 50 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2020.
All research outputs
#6,446,325
of 25,382,440 outputs
Outputs from Frontiers in immunology
#6,733
of 31,537 outputs
Outputs of similar age
#115,449
of 446,708 outputs
Outputs of similar age from Frontiers in immunology
#165
of 592 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 446,708 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 592 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.