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Epstein–Barr Virus-Specific Immune Control by Innate Lymphocytes

Overview of attention for article published in Frontiers in immunology, November 2017
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Title
Epstein–Barr Virus-Specific Immune Control by Innate Lymphocytes
Published in
Frontiers in immunology, November 2017
DOI 10.3389/fimmu.2017.01658
Pubmed ID
Authors

Christian Münz

Abstract

Epstein-Barr virus (EBV) is a potent B cell transforming pathogen in humans. In most persistently EBV-infected individuals, potent cytotoxic lymphocyte responses prevent EBV-associated pathologies. In addition to comprehensive adaptive T cell responses, several innate lymphocyte populations seem to target different stages of EBV infection and are compromised in primary immunodeficiencies that render individuals susceptible to symptomatic EBV infection. In this mini-review, I will highlight the functions of natural killer, γδ T cells, and natural killer T cells during innate immune responses to EBV. These innate lymphocyte populations seem to restrict both lytic replication and transforming latent EBV antigen expression. The mechanisms underlying the recognition of these different EBV infection programs by the respective innate lymphocytes are just starting to become unraveled, but will provide immunotherapeutic strategies to target pathologies that are associated with the different EBV infection programs.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 61 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 21%
Student > Master 12 20%
Researcher 11 18%
Student > Bachelor 5 8%
Other 4 7%
Other 4 7%
Unknown 12 20%
Readers by discipline Count As %
Immunology and Microbiology 21 34%
Biochemistry, Genetics and Molecular Biology 10 16%
Medicine and Dentistry 9 15%
Agricultural and Biological Sciences 3 5%
Mathematics 1 2%
Other 5 8%
Unknown 12 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 September 2021.
All research outputs
#20,031,563
of 25,483,400 outputs
Outputs from Frontiers in immunology
#22,700
of 31,801 outputs
Outputs of similar age
#322,141
of 446,825 outputs
Outputs of similar age from Frontiers in immunology
#460
of 589 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,801 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 446,825 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 589 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.