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Unraveling Natural Killer T-Cells Development

Overview of attention for article published in Frontiers in immunology, January 2018
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Title
Unraveling Natural Killer T-Cells Development
Published in
Frontiers in immunology, January 2018
DOI 10.3389/fimmu.2017.01950
Pubmed ID
Authors

Sabrina Bianca Bennstein

Abstract

Natural killer T-cells are a subset of innate-like T-cells with the ability to bridge innate and adaptive immunity. There is great interest in harnessing these cells to improve tumor therapy; however, greater understanding of invariant NKT (iNKT) cell biology is needed. The first step is to learn more about NKT development within the thymus. Recent studies suggest lineage separation of murine iNKT cells into iNKT1, iNKT2, and iNKT17 cells instead of shared developmental stages. This review will focus on these new studies and will discuss the evidence for lineage separation in contrast to shared developmental stages. The author will also highlight the classifications of murine iNKT cells according to identified transcription factors and cytokine production, and will discuss transcriptional and posttranscriptional regulations, and the role of mammalian target of rapamycin. Finally, the importance of these findings for human cancer therapy will be briefly discussed.

X Demographics

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The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 109 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 20%
Researcher 14 13%
Student > Bachelor 13 12%
Student > Master 13 12%
Student > Doctoral Student 6 6%
Other 14 13%
Unknown 27 25%
Readers by discipline Count As %
Immunology and Microbiology 32 29%
Agricultural and Biological Sciences 20 18%
Biochemistry, Genetics and Molecular Biology 16 15%
Medicine and Dentistry 9 8%
Economics, Econometrics and Finance 1 <1%
Other 3 3%
Unknown 28 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2020.
All research outputs
#14,708,824
of 25,547,324 outputs
Outputs from Frontiers in immunology
#12,491
of 31,950 outputs
Outputs of similar age
#224,636
of 451,933 outputs
Outputs of similar age from Frontiers in immunology
#316
of 615 outputs
Altmetric has tracked 25,547,324 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,950 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 451,933 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 615 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.