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The Interface between Fungal Biofilms and Innate Immunity

Overview of attention for article published in Frontiers in immunology, January 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (74th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

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15 X users

Citations

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105 Dimensions

Readers on

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159 Mendeley
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Title
The Interface between Fungal Biofilms and Innate Immunity
Published in
Frontiers in immunology, January 2018
DOI 10.3389/fimmu.2017.01968
Pubmed ID
Authors

John F. Kernien, Brendan D. Snarr, Donald C. Sheppard, Jeniel E. Nett

Abstract

Fungal biofilms are communities of adherent cells surrounded by an extracellular matrix. These biofilms are commonly found during infection caused by a variety of fungal pathogens. Clinically, biofilm infections can be extremely difficult to eradicate due to their resistance to antifungals and host defenses. Biofilm formation can protect fungal pathogens from many aspects of the innate immune system, including killing by neutrophils and monocytes. Altered immune recognition during this phase of growth is also evident by changes in the cytokine profiles of monocytes and macrophages exposed to biofilm. In this manuscript, we review the host response to fungal biofilms, focusing on how these structures are recognized by the innate immune system. Biofilms formed by Candida, Aspergillus, and Cryptococcus have received the most attention and are highlighted. We describe common themes involved in the resilience of fungal biofilms to host immunity and give examples of biofilm defenses that are pathogen-specific.

X Demographics

X Demographics

The data shown below were collected from the profiles of 15 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 159 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 159 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 23%
Student > Master 16 10%
Student > Bachelor 15 9%
Researcher 15 9%
Student > Doctoral Student 7 4%
Other 22 14%
Unknown 47 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 32 20%
Immunology and Microbiology 24 15%
Agricultural and Biological Sciences 18 11%
Medicine and Dentistry 12 8%
Engineering 6 4%
Other 8 5%
Unknown 59 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 August 2023.
All research outputs
#5,449,088
of 25,382,440 outputs
Outputs from Frontiers in immunology
#6,173
of 31,537 outputs
Outputs of similar age
#110,627
of 451,175 outputs
Outputs of similar age from Frontiers in immunology
#172
of 615 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 451,175 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 615 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.