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Tissue-Dependent Tumor Microenvironments and Their Impact on Immunotherapy Responses

Overview of attention for article published in Frontiers in immunology, January 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

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1 news outlet
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15 X users

Citations

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127 Dimensions

Readers on

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151 Mendeley
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Title
Tissue-Dependent Tumor Microenvironments and Their Impact on Immunotherapy Responses
Published in
Frontiers in immunology, January 2018
DOI 10.3389/fimmu.2018.00070
Pubmed ID
Authors

Amanda J. Oliver, Peter K. H. Lau, Ashleigh S. Unsworth, Sherene Loi, Phillip K. Darcy, Michael H. Kershaw, Clare Y. Slaney

Abstract

Recent advances in cancer immunology have led to a better understanding of the role of the tumor microenvironment (TME) in tumor initiation, progression, and metastasis. Tumors can occur at many locations within the body and coevolution between malignant tumor cells and non-malignant cells sculpts the TME at these sites. It has become increasingly clear that there are specific differences of the TMEs at different anatomical locations, and these tissue-specific TMEs regulate tumor growth, determine metastatic progression, and impact on the outcome of therapy responses. Herein, we review the scientific advances in understanding tissue-specific TMEs, discuss their impact on immunotherapeutic response, and assess the current clinical knowledge in this emerging field. A deeper understanding of the tissue-specific TME will help to develop effective immunotherapies against tumors and their metastases and assist in predicting clinical outcomes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 15 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 151 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 33 22%
Researcher 23 15%
Student > Bachelor 16 11%
Other 9 6%
Student > Master 9 6%
Other 17 11%
Unknown 44 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 28 19%
Immunology and Microbiology 26 17%
Medicine and Dentistry 24 16%
Agricultural and Biological Sciences 10 7%
Engineering 4 3%
Other 13 9%
Unknown 46 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2022.
All research outputs
#1,930,599
of 25,382,440 outputs
Outputs from Frontiers in immunology
#1,818
of 31,537 outputs
Outputs of similar age
#44,294
of 448,910 outputs
Outputs of similar age from Frontiers in immunology
#61
of 644 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 448,910 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 644 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.