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Targeting IgE Antibodies by Immunoadsorption in Atopic Dermatitis

Overview of attention for article published in Frontiers in immunology, February 2018
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Title
Targeting IgE Antibodies by Immunoadsorption in Atopic Dermatitis
Published in
Frontiers in immunology, February 2018
DOI 10.3389/fimmu.2018.00254
Pubmed ID
Authors

Michael Kasperkiewicz, Enno Schmidt, Ralf J. Ludwig, Detlef Zillikens

Abstract

One major hallmark of atopic dermatitis (AD) is the elevated level of total serum IgE, which has been reported to be partly of the autoreactive type in a subset of patients. Immunoadsorption (IA) has been successfully applied in various classical autoantibody-mediated diseases such as pemphigus. Recent reports proposed the use of IA also for patients with severe AD and high total serum IgE levels. In this mini-review, we summarize the current knowledge about this novel treatment approach for AD and briefly discuss the so far incompletely known role of autoreactive IgE as potential target of IA therapy in this common inflammatory skin disorder.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 17%
Student > Bachelor 4 10%
Student > Ph. D. Student 4 10%
Student > Doctoral Student 3 7%
Professor 2 5%
Other 5 12%
Unknown 16 39%
Readers by discipline Count As %
Medicine and Dentistry 14 34%
Immunology and Microbiology 6 15%
Nursing and Health Professions 2 5%
Unspecified 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 3 7%
Unknown 14 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 March 2018.
All research outputs
#16,827,702
of 25,523,622 outputs
Outputs from Frontiers in immunology
#18,498
of 31,887 outputs
Outputs of similar age
#212,206
of 344,590 outputs
Outputs of similar age from Frontiers in immunology
#478
of 694 outputs
Altmetric has tracked 25,523,622 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,887 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,590 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 694 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.