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B Cell Modulation Strategies in Autoimmune Diseases: New Concepts

Overview of attention for article published in Frontiers in immunology, April 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

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1 news outlet
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13 X users
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1 patent
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1 research highlight platform

Citations

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95 Dimensions

Readers on

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143 Mendeley
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Title
B Cell Modulation Strategies in Autoimmune Diseases: New Concepts
Published in
Frontiers in immunology, April 2018
DOI 10.3389/fimmu.2018.00622
Pubmed ID
Authors

Philippe Musette, Jean David Bouaziz

Abstract

B cells are major effector cells in autoimmunity through antibody production, T cell help and pro-inflammatory cytokine production. Major advances have been made in human B cell biology knowledge using rituximab and type II new anti-CD20 antibodies, anti-CD19 antibodies, anti-CD22 antibodies, autoantigen specific B cell depleting therapy (chimeric antigen receptor T cells), and B cell receptor signaling inhibition (Bruton's tyrosine kinase inhibitors). However, in certain circumstances B cell depleting therapy may lead to the worsening of the autoimmune disease which is in accordance with the existence of a regulatory B cell population. Current concepts and future directions for B cell modulating therapies in autoimmune diseases with a special focus on pemphigus are discussed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 143 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 15%
Student > Master 19 13%
Researcher 15 10%
Student > Doctoral Student 15 10%
Student > Bachelor 12 8%
Other 27 19%
Unknown 34 24%
Readers by discipline Count As %
Medicine and Dentistry 28 20%
Biochemistry, Genetics and Molecular Biology 23 16%
Immunology and Microbiology 19 13%
Agricultural and Biological Sciences 14 10%
Engineering 4 3%
Other 14 10%
Unknown 41 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 August 2023.
All research outputs
#1,919,699
of 25,382,440 outputs
Outputs from Frontiers in immunology
#1,807
of 31,537 outputs
Outputs of similar age
#40,568
of 342,076 outputs
Outputs of similar age from Frontiers in immunology
#53
of 698 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,076 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 698 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.