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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease
|
|---|---|
| Published in |
Frontiers in immunology, April 2018
|
| DOI | 10.3389/fimmu.2018.00693 |
| Pubmed ID | |
| Authors |
Shu-Ling Wang, Bo-Zong Shao, Sheng-Bing Zhao, Jun Fang, Lun Gu, Chao-Yu Miao, Zhao-Shen Li, Yu Bai |
| Abstract |
Intestinal mucosal barrier, mainly consisting of the mucus layer and epithelium, functions in absorbing nutrition as well as prevention of the invasion of pathogenic microorganisms. Paneth cell, an important component of mucosal barrier, plays a vital role in maintaining the intestinal homeostasis by producing antimicrobial materials and controlling the host-commensal balance. Current evidence shows that the dysfunction of intestinal mucosal barrier, especially Paneth cell, participates in the onset and progression of inflammatory bowel disease (IBD). Autophagy, a cellular stress response, involves various physiological processes, such as secretion of proteins, production of antimicrobial peptides, and degradation of aberrant organelles or proteins. In the recent years, the roles of autophagy in the pathogenesis of IBD have been increasingly studied. Here in this review, we mainly focus on describing the roles of Paneth cell autophagy in IBD as well as several popular autophagy-related genetic variants in Penath cell and the related therapeutic strategies against IBD. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 1 | 33% |
| Switzerland | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 86 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 16% |
| Student > Master | 11 | 13% |
| Student > Bachelor | 11 | 13% |
| Researcher | 6 | 7% |
| Professor | 5 | 6% |
| Other | 13 | 15% |
| Unknown | 26 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 16% |
| Agricultural and Biological Sciences | 13 | 15% |
| Biochemistry, Genetics and Molecular Biology | 12 | 14% |
| Immunology and Microbiology | 12 | 14% |
| Arts and Humanities | 1 | 1% |
| Other | 3 | 3% |
| Unknown | 31 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2021.
All research outputs
#3,255,473
of 25,382,440 outputs
Outputs from Frontiers in immunology
#3,502
of 31,537 outputs
Outputs of similar age
#64,432
of 343,387 outputs
Outputs of similar age from Frontiers in immunology
#108
of 701 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,387 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 701 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.