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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Targeting B Cells and Plasma Cells in Autoimmune Diseases
|
|---|---|
| Published in |
Frontiers in immunology, April 2018
|
| DOI | 10.3389/fimmu.2018.00835 |
| Pubmed ID | |
| Authors |
Katharina Hofmann, Ann-Katrin Clauder, Rudolf Armin Manz |
| Abstract |
Success with B cell depletion using rituximab has proven the concept that B lineage cells represent a valid target for the treatment of autoimmune diseases, and has promoted the development of other B cell targeting agents. Present data confirm that B cell depletion is beneficial in various autoimmune disorders and also show that it can worsen the disease course in some patients. These findings suggest that B lineage cells not only produce pathogenic autoantibodies, but also significantly contribute to the regulation of inflammation. In this review, we will discuss the multiple pro- and anti-inflammatory roles of B lineage cells play in autoimmune diseases, in the context of recent findings using B lineage targeting therapies. |
X Demographics
The data shown below were collected from the profiles of 18 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 17% |
| Italy | 1 | 6% |
| Slovakia | 1 | 6% |
| Malaysia | 1 | 6% |
| India | 1 | 6% |
| Colombia | 1 | 6% |
| Switzerland | 1 | 6% |
| Unknown | 9 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 13 | 72% |
| Practitioners (doctors, other healthcare professionals) | 3 | 17% |
| Scientists | 2 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 250 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 250 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 41 | 16% |
| Researcher | 36 | 14% |
| Student > Master | 33 | 13% |
| Student > Bachelor | 25 | 10% |
| Student > Doctoral Student | 16 | 6% |
| Other | 34 | 14% |
| Unknown | 65 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 43 | 17% |
| Immunology and Microbiology | 38 | 15% |
| Biochemistry, Genetics and Molecular Biology | 28 | 11% |
| Agricultural and Biological Sciences | 22 | 9% |
| Neuroscience | 11 | 4% |
| Other | 27 | 11% |
| Unknown | 81 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2019.
All research outputs
#4,083,782
of 25,382,440 outputs
Outputs from Frontiers in immunology
#4,327
of 31,537 outputs
Outputs of similar age
#74,328
of 340,059 outputs
Outputs of similar age from Frontiers in immunology
#135
of 707 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,059 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 707 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.