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Unraveling the Mechanisms of Cutaneous Graft-Versus-Host Disease

Overview of attention for article published in Frontiers in immunology, May 2018
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Title
Unraveling the Mechanisms of Cutaneous Graft-Versus-Host Disease
Published in
Frontiers in immunology, May 2018
DOI 10.3389/fimmu.2018.00963
Pubmed ID
Authors

Pedro Santos e Sousa, Clare L. Bennett, Ronjon Chakraverty

Abstract

The skin is the most common target organ affected by graft-versus-host disease (GVHD), with severity and response to therapy representing important predictors of patient survival. Although many of the initiating events in GVHD pathogenesis have been defined, less is known about why treatment resistance occurs or why there is often a permanent failure to restore tissue homeostasis. Emerging data suggest that the unique immune microenvironment in the skin is responsible for defining location- and context-specific mechanisms of injury that are distinct from those involved in other target organs. In this review, we address recent advances in our understanding of GVHD biology in the skin and outline the new research themes that will ultimately enable design of precision therapies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 54 100%

Demographic breakdown

Readers by professional status Count As %
Other 12 22%
Researcher 7 13%
Student > Ph. D. Student 7 13%
Student > Bachelor 5 9%
Student > Postgraduate 2 4%
Other 3 6%
Unknown 18 33%
Readers by discipline Count As %
Medicine and Dentistry 16 30%
Biochemistry, Genetics and Molecular Biology 8 15%
Immunology and Microbiology 4 7%
Agricultural and Biological Sciences 3 6%
Physics and Astronomy 1 2%
Other 3 6%
Unknown 19 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2018.
All research outputs
#16,053,755
of 25,382,440 outputs
Outputs from Frontiers in immunology
#16,721
of 31,537 outputs
Outputs of similar age
#196,053
of 338,899 outputs
Outputs of similar age from Frontiers in immunology
#455
of 711 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 338,899 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 711 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.