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Lipid Droplet, a Key Player in Host-Parasite Interactions

Overview of attention for article published in Frontiers in immunology, May 2018
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Title
Lipid Droplet, a Key Player in Host-Parasite Interactions
Published in
Frontiers in immunology, May 2018
DOI 10.3389/fimmu.2018.01022
Pubmed ID
Authors

Adriana Lima Vallochi, Livia Teixeira, Karina da Silva Oliveira, Clarissa Menezes Maya-Monteiro, Patricia T. Bozza

Abstract

Lipid droplets (lipid bodies, LDs) are dynamic organelles that have important roles in regulating lipid metabolism, energy homeostasis, cell signaling, membrane trafficking, and inflammation. LD biogenesis, composition, and functions are highly regulated and may vary according to the stimuli, cell type, activation state, and inflammatory environment. Increased cytoplasmic LDs are frequently observed in leukocytes and other cells in a number of infectious diseases. Accumulating evidence reveals LDs participation in fundamental mechanisms of host-pathogen interactions, including cell signaling and immunity. LDs are sources of eicosanoid production, and may participate in different aspects of innate signaling and antigen presentation. In addition, intracellular pathogens evolved mechanisms to subvert host metabolism and may use host LDs, as ways of immune evasion and nutrients source. Here, we review mechanisms of LDs biogenesis and their contributions to the infection progress, and discuss the latest discoveries on mechanisms and pathways involving LDs roles as regulators of the immune response to protozoan infection.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 135 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 23 17%
Student > Bachelor 20 15%
Researcher 13 10%
Student > Master 11 8%
Student > Doctoral Student 10 7%
Other 13 10%
Unknown 45 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 31 23%
Immunology and Microbiology 22 16%
Agricultural and Biological Sciences 19 14%
Pharmacology, Toxicology and Pharmaceutical Science 4 3%
Chemistry 4 3%
Other 9 7%
Unknown 46 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2018.
All research outputs
#22,963,239
of 25,604,262 outputs
Outputs from Frontiers in immunology
#27,856
of 32,042 outputs
Outputs of similar age
#302,673
of 344,486 outputs
Outputs of similar age from Frontiers in immunology
#687
of 752 outputs
Altmetric has tracked 25,604,262 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 32,042 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 752 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.