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Betaine in Inflammation: Mechanistic Aspects and Applications

Overview of attention for article published in Frontiers in immunology, May 2018
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
4 news outlets
twitter
14 X users
patent
1 patent
video
5 YouTube creators

Citations

dimensions_citation
277 Dimensions

Readers on

mendeley
236 Mendeley
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Title
Betaine in Inflammation: Mechanistic Aspects and Applications
Published in
Frontiers in immunology, May 2018
DOI 10.3389/fimmu.2018.01070
Pubmed ID
Authors

Guangfu Zhao, Fang He, Chenlu Wu, Pan Li, Nengzhang Li, Jinping Deng, Guoqiang Zhu, Wenkai Ren, Yuanyi Peng

Abstract

Betaine is known as trimethylglycine and is widely distributed in animals, plants, and microorganisms. Betaine is known to function physiologically as an important osmoprotectant and methyl group donor. Accumulating evidence has shown that betaine has anti-inflammatory functions in numerous diseases. Mechanistically, betaine ameliorates sulfur amino acid metabolism against oxidative stress, inhibits nuclear factor-κB activity and NLRP3 inflammasome activation, regulates energy metabolism, and mitigates endoplasmic reticulum stress and apoptosis. Consequently, betaine has beneficial actions in several human diseases, such as obesity, diabetes, cancer, and Alzheimer's disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 236 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 236 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 13%
Student > Master 27 11%
Student > Bachelor 23 10%
Researcher 14 6%
Other 10 4%
Other 33 14%
Unknown 98 42%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 49 21%
Agricultural and Biological Sciences 19 8%
Medicine and Dentistry 13 6%
Veterinary Science and Veterinary Medicine 9 4%
Neuroscience 6 3%
Other 33 14%
Unknown 107 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 52. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2024.
All research outputs
#820,651
of 25,490,562 outputs
Outputs from Frontiers in immunology
#721
of 31,813 outputs
Outputs of similar age
#17,997
of 344,318 outputs
Outputs of similar age from Frontiers in immunology
#28
of 752 outputs
Altmetric has tracked 25,490,562 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,813 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,318 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 752 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.