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Mechanisms of Fish Macrophage Antimicrobial Immunity

Overview of attention for article published in Frontiers in immunology, May 2018
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Title
Mechanisms of Fish Macrophage Antimicrobial Immunity
Published in
Frontiers in immunology, May 2018
DOI 10.3389/fimmu.2018.01105
Pubmed ID
Authors

Leon Grayfer, Baris Kerimoglu, Amulya Yaparla, Jordan W. Hodgkinson, Jiasong Xie, Miodrag Belosevic

Abstract

Overcrowding conditions and temperatures shifts regularly manifest in large-scale infections of farmed fish, resulting in economic losses for the global aquaculture industries. Increased understanding of the functional mechanisms of fish antimicrobial host defenses is an important step forward in prevention of pathogen-induced morbidity and mortality in aquaculture setting. Like other vertebrates, macrophage-lineage cells are integral to fish immune responses and for this reason, much of the recent fish immunology research has focused on fish macrophage biology. These studies have revealed notable similarities as well as striking differences in the molecular strategies by which fish and higher vertebrates control their respective macrophage polarization and functionality. In this review, we address the current understanding of the biological mechanisms of teleost macrophage functional heterogeneity and immunity, focusing on the key cytokine regulators that control fish macrophage development and their antimicrobial armamentarium.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 170 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 170 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 16%
Student > Master 26 15%
Researcher 18 11%
Student > Bachelor 15 9%
Student > Doctoral Student 6 4%
Other 17 10%
Unknown 61 36%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 20%
Biochemistry, Genetics and Molecular Biology 27 16%
Immunology and Microbiology 21 12%
Veterinary Science and Veterinary Medicine 11 6%
Medicine and Dentistry 2 1%
Other 5 3%
Unknown 70 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2018.
All research outputs
#20,838,437
of 25,604,262 outputs
Outputs from Frontiers in immunology
#25,102
of 32,042 outputs
Outputs of similar age
#269,085
of 344,988 outputs
Outputs of similar age from Frontiers in immunology
#636
of 748 outputs
Altmetric has tracked 25,604,262 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 32,042 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,988 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 748 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.