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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Confluence of Sex Hormones and Aging on Immunity
|
|---|---|
| Published in |
Frontiers in immunology, June 2018
|
| DOI | 10.3389/fimmu.2018.01269 |
| Pubmed ID | |
| Authors |
Melanie R. Gubbels Bupp, Tanvi Potluri, Ashley L. Fink, Sabra L. Klein |
| Abstract |
The immune systems of post-pubescent males and females differ significantly with profound consequences to health and disease. In many cases, sex-specific differences in the immune responses of young adults are also apparent in aged men and women. Moreover, as in young adults, aged women develop several late-adult onset autoimmune conditions more frequently than do men, while aged men continue to develop many cancers to a greater extent than aged women. However, sex differences in the immune systems of aged individuals have not been extensively investigated and data addressing the effectiveness of vaccinations and immunotherapies in aged men and women are scarce. In this review, we evaluate age- and sex hormone-related changes to innate and adaptive immunity, with consideration about how this impacts age- and sex-associated changes in the incidence and pathogenesis of autoimmunity and cancer as well as the efficacy of vaccination and cancer immunotherapy. We conclude that future preclinical and clinical studies should consider age and sex to better understand the ways in which these characteristics intersect with immune function and the resulting consequences for autoimmunity, cancer, and therapeutic interventions. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 232 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 232 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 12% |
| Student > Master | 27 | 12% |
| Researcher | 26 | 11% |
| Student > Bachelor | 26 | 11% |
| Student > Postgraduate | 14 | 6% |
| Other | 40 | 17% |
| Unknown | 72 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 49 | 21% |
| Biochemistry, Genetics and Molecular Biology | 28 | 12% |
| Immunology and Microbiology | 18 | 8% |
| Agricultural and Biological Sciences | 18 | 8% |
| Neuroscience | 8 | 3% |
| Other | 23 | 10% |
| Unknown | 88 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2024.
All research outputs
#3,200,318
of 25,736,439 outputs
Outputs from Frontiers in immunology
#3,401
of 32,276 outputs
Outputs of similar age
#61,345
of 343,876 outputs
Outputs of similar age from Frontiers in immunology
#110
of 744 outputs
Altmetric has tracked 25,736,439 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32,276 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,876 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 744 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.