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The Role of Mitophagy in Innate Immunity

Overview of attention for article published in Frontiers in immunology, June 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

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20 X users
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1 Wikipedia page

Readers on

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187 Mendeley
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Title
The Role of Mitophagy in Innate Immunity
Published in
Frontiers in immunology, June 2018
DOI 10.3389/fimmu.2018.01283
Pubmed ID
Authors

Ilias Gkikas, Konstantinos Palikaras, Nektarios Tavernarakis

Abstract

Mitochondria are cellular organelles essential for multiple biological processes, including energy production, metabolites biosynthesis, cell death, and immunological responses among others. Recent advances in the field of immunology research reveal the pivotal role of energy metabolism in innate immune cells fate and function. Therefore, the maintenance of mitochondrial network integrity and activity is a prerequisite for immune system homeostasis. Mitochondrial selective autophagy, known as mitophagy, surveils mitochondrial population eliminating superfluous and/or impaired organelles and mediating cellular survival and viability in response to injury/trauma and infection. Defective removal of damaged mitochondria leads to hyperactivation of inflammatory signaling pathways and subsequently to chronic systemic inflammation and development of inflammatory diseases. Here, we review the molecular mechanisms of mitophagy and highlight its critical role in the innate immune system homeostasis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 187 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 187 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 17%
Researcher 29 16%
Student > Master 23 12%
Student > Bachelor 19 10%
Student > Doctoral Student 13 7%
Other 25 13%
Unknown 47 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 61 33%
Agricultural and Biological Sciences 14 7%
Immunology and Microbiology 14 7%
Neuroscience 13 7%
Medicine and Dentistry 11 6%
Other 24 13%
Unknown 50 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 May 2023.
All research outputs
#2,796,385
of 25,382,440 outputs
Outputs from Frontiers in immunology
#2,874
of 31,537 outputs
Outputs of similar age
#55,837
of 343,126 outputs
Outputs of similar age from Frontiers in immunology
#98
of 745 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,126 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 745 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.