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Adverse Effects of Immunoglobulin Therapy

Overview of attention for article published in Frontiers in immunology, June 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
15 X users
facebook
2 Facebook pages
video
1 YouTube creator

Readers on

mendeley
323 Mendeley
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Title
Adverse Effects of Immunoglobulin Therapy
Published in
Frontiers in immunology, June 2018
DOI 10.3389/fimmu.2018.01299
Pubmed ID
Authors

Yi Guo, Xin Tian, Xuefeng Wang, Zheng Xiao

Abstract

Immunoglobulin has been widely used in a variety of diseases, including primary and secondary immunodeficiency diseases, neuromuscular diseases, and Kawasaki disease. Although a large number of clinical trials have demonstrated that immunoglobulin is effective and well tolerated, various adverse effects have been reported. The majority of these events, such as flushing, headache, malaise, fever, chills, fatigue and lethargy, are transient and mild. However, some rare side effects, including renal impairment, thrombosis, arrhythmia, aseptic meningitis, hemolytic anemia, and transfusion-related acute lung injury (TRALI), are serious. These adverse effects are associated with specific immunoglobulin preparations and individual differences. Performing an early assessment of risk factors, infusing at a slow rate, premedicating, and switching from intravenous immunoglobulin (IVIG) to subcutaneous immunoglobulin (SCIG) can minimize these adverse effects. Adverse effects are rarely disabling or fatal, treatment mainly involves supportive measures, and the majority of affected patients have a good prognosis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 15 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 323 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 323 100%

Demographic breakdown

Readers by professional status Count As %
Other 43 13%
Student > Bachelor 31 10%
Researcher 27 8%
Student > Doctoral Student 27 8%
Student > Master 24 7%
Other 52 16%
Unknown 119 37%
Readers by discipline Count As %
Medicine and Dentistry 103 32%
Pharmacology, Toxicology and Pharmaceutical Science 17 5%
Neuroscience 17 5%
Biochemistry, Genetics and Molecular Biology 13 4%
Immunology and Microbiology 12 4%
Other 35 11%
Unknown 126 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 March 2024.
All research outputs
#1,631,348
of 25,706,302 outputs
Outputs from Frontiers in immunology
#1,474
of 32,218 outputs
Outputs of similar age
#33,787
of 343,171 outputs
Outputs of similar age from Frontiers in immunology
#56
of 744 outputs
Altmetric has tracked 25,706,302 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32,218 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,171 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 744 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.