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The Circadian Clock Drives Mast Cell Functions in Allergic Reactions

Overview of attention for article published in Frontiers in immunology, July 2018
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
2 news outlets
twitter
112 X users
facebook
8 Facebook pages

Citations

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32 Dimensions

Readers on

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70 Mendeley
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Title
The Circadian Clock Drives Mast Cell Functions in Allergic Reactions
Published in
Frontiers in immunology, July 2018
DOI 10.3389/fimmu.2018.01526
Pubmed ID
Authors

Pia Christ, Anna Sergeevna Sowa, Oren Froy, Axel Lorentz

Abstract

Allergic diseases are known to vary in the severity of their symptoms throughout the day/night cycle. This rhythmicity is also observed in mast cell function and responsiveness. Mast cells are key effector cells of allergic reactions and release cytokines, chemokines, and important inflammatory mediators such as histamine, which have been shown to display diurnal variation. Recent research clarified that mast cells are controlled by their internal clock-which is regulated by a specific set of clock genes-as well as external factors such as light sensed by the suprachiasmatic nuclei, hormonal status, or diet. Here, we give an overview of the connections between circadian clock, mast cells, and allergic disease. Further work aimed at studying the role of chronotherapy/chronomedicine should take into account this rhythmic nature of not only mast cells but also the immune responses generated by mast cell signaling.

X Demographics

X Demographics

The data shown below were collected from the profiles of 112 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 70 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 14%
Researcher 8 11%
Other 7 10%
Student > Bachelor 7 10%
Student > Ph. D. Student 5 7%
Other 11 16%
Unknown 22 31%
Readers by discipline Count As %
Medicine and Dentistry 17 24%
Agricultural and Biological Sciences 7 10%
Immunology and Microbiology 5 7%
Nursing and Health Professions 5 7%
Biochemistry, Genetics and Molecular Biology 4 6%
Other 8 11%
Unknown 24 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 89. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2024.
All research outputs
#488,893
of 25,729,842 outputs
Outputs from Frontiers in immunology
#451
of 32,274 outputs
Outputs of similar age
#10,442
of 342,013 outputs
Outputs of similar age from Frontiers in immunology
#20
of 738 outputs
Altmetric has tracked 25,729,842 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32,274 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,013 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 738 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.